EVALUATION OF THE ANTIBACTERIAL ACTIVITY OF Crotalus durissus terrificus CRUDE VENOM
نویسندگان
چکیده
منابع مشابه
Crotalus durissus terrificus venom as a source of antitumoral agents
The basic knowledge on neoplasms is increasing quickly; however, few advances have been achieved in clinical therapy against tumors. For this reason, the development of alternative drugs is relevant in the attempt to improve prognosis and to increase patients’ survival. Snake venoms are natural sources of bioactive substances with therapeutic potential. The objective of this work was to identif...
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Many studies have reported the occurrence of lethal acute renal failure after snakebites. The aim of the present investigation was to determine alterations in renal function produced by Crotalus durissus terrificus venom and crotoxin as well as the histological alterations induced by these venoms. Isolated kidneys from Wistar rats weighing 240 to 280 g were perfused with Krebs-Henseleit solutio...
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Herein we report that crotamine, a small lysine- and cysteine-rich protein from the venom of the South American rattlesnake, can rapidly penetrate into different cell types and mouse blastocysts in vitro. In vivo crotamine strongly labels cells from mouse bone marrow and spleen and from peritoneal liquid, as shown by fluorescent confocal laser-scanning microscopy. Nuclear localization of crotam...
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ژورنال
عنوان ژورنال: Ciência Animal Brasileira
سال: 2018
ISSN: 1809-6891,1518-2797
DOI: 10.1590/1809-6891v19e-51322